Synthesis of D-Apio-β-D-furanosyl Maleimide, an Analogue of Showdomycin with Transposed Hydroxymethyl Group

Article abstract of DOI:10.1007/BF00807307

Apioshowdomycin (3-(D-apio-β-D-furanosyl)-1H-pyrrole-2,5-dione, 2) has been prepared as an analogue of the C-nucleoside showdomycin (1) in eight steps and with 5% overall yield, starting from 2,3-O-isopropylidene-D-apio-β-D-furanose (3).