Synthesis and reactivity of alkyl (4-aminothien-3-yl)carbamates

Article abstract of DOI:10.1016/S0040-4020(97)00681-9

Monocarbamates 2 have been prepared from 3,4-diaminothiophene 1 and were alkylated on the thiophene nucleus using an aldehyde and selenophenol, under acid catalysis. This reaction has allowed the access to 2-alkyl 3,4-diaminothiophenes 9, 3,5-diaminodithieno[3,2-b:2',3'-e]pyridines 10 and 1-alkyl thieno[3,4-d]imidazolones 13.