Synthesis of bis-abasic cyclic dinucleotide, bis-(3→5)-cyclic bis(1,4-anhydro-2-deoxy-D-erythro-pentitol-3-phosphate), an inhibitor of HIV-1 integrase

Article abstract of DOI:10.1016/S0040-4020(97)00363-3

Bis-abasic cyclic dinucleotide, bis-(3→5)-cyclic bis(1,4-anhydro-2-deoxy-D-erythro-pentitol-3-phosphate) (1), was prepared from 2-deoxy-D-ribose in nine convergent steps, in 18% overall yield.