Enantioselective synthesis of S-substituted ω-amino-α-thiohydroxycarboxylic acids via sulfenylation of 2-(ω-aminoalkyl)-oxazolines

Article abstract of DOI:10.1016/S0957-4166(97)00259-0

Optically active ω-benzenesulfonylamino-α-methylthio- and ω-benzenesulfonylamino-α-phenylthiocarboxylic acids 7 were synthesized by stereoselective α-sulfenylation of 2-(ω-benzenesulfonylaminoalkyl)-1,3-oxazolines 3 with disulfides in the presence of LDA,