Tetrahedron Letters p. 7131 - 7134 (1997)
Update date:2022-07-29
Topics:
Houpis, Ioannis N.
Molina, Audrey
Dorziotis, Ilias
Reamer, Robert A.
Volante
Reider, Paul J.
Ph3lZnMgCl was added to the optically pure sulfoxide 3 in the presence of Ni(acac)2 to give, after desulfurization, the phosphodiesterase N inhibitor 1 in good yield and 92% enantiomeric excess.
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