Synlett p. 1294 - 1296 (1997)
Update date:2022-08-02
Topics:
Defoin, Albert
Sifferlen, Thierry
Streith, Jacques
Base-catalysed rearrangement of the oxazine-carboxylate 8, obtained from pentadienoic acid 4 by asymmetric hetero-Diels-Alder reaction followed by simple chemical transformations, led to the protected trihydroxy-proline 9. Using various reduction conditions, the potent glycosidase inhibitors 1,4-dideoxy-1,4-imino-D-lyxitol D-1 and 1,4-dideoxy-1,4-imino-L-ribitol L-2 were obtained.
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Doi:10.1016/S0022-1139(00)82302-7
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