New approach to the synthesis of dibenzodithia- and benzothiaazacrown ethers via the aromatization of 2-alkylthio(arylthio)-cyclohexanes during bromination

Article abstract of DOI:10.1007/BF02290756

A new scheme for the synthesis of dibenzodithiacrown ethers is proposed based on the use of substituted phenol derivatives as intermediates, prepared by aromatization of 2-alkylthio(arylthio)cyclohexanes during bromination. 1,7-Dithia-8,9,17,18-dibenzo-18-crown-6 and 1,10-dithia-11,12,20,21-dibenzo-21-crown-7 without isomers relative to position of the sulfur atoms have been synthesized, and also new thiadiazamacroheterocycles - 1,4,7-trioxa-10,19-dithia-13,16-diaza-12,17-dioxo-8,9,14,15,20,21- tribenzoheneicosane and 1,4,7,10-tetraoxa-13,22-dithia-16,19-diaza-15,20-dioxo-11,12,17,18,23,24- tribenzotetracosane. 1997 Plenum Publishing Corporation.