Synthesis of 3′-thioribouridine, 3′-thioribocytidine, and their phosphoramidites

Article abstract of DOI:10.1080/07328319708006225

3′-Thio-3′-deoxyribonucleosides (U and C) have been synthesized via Vorbruggen-type glycosylation with 3-S-benzoyl-5-O-toluoyl-1,2-O-diacetylfuranose, which was obtained from 1,2-O-isopropylidene-5-O-toluoyl-3-O-trifluoromethanesulfonyl-α-D- xylofuranose. 3′-Thio-3′-deoxyuridine has been converted to its phosphoramidite. Copyright

Full text of DOI:10.1080/07328319708006225

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Synthesis of 3′-Thioribouridine,
3′-Thioribocytidine, and Their
Phosphoramidites
Sengen Sun a & Joseph A. Piccirilli a
a Howard Hughes Medical Institute, Department of Chemistry
and Department of Biochemistry and Molecular Biology , The
University of Chicago , 5841 South Maryland Avenue, Room
N101, Chicago, Illinois, 60637
Published online: 16 Aug 2006.
To cite this article: Sengen Sun & Joseph A. Piccirilli (1997) Synthesis of 3′-Thioribouridine, 3′-
Thioribocytidine, and Their Phosphoramidites, Nucleosides and Nucleotides, 16:7-9, 1543-1545,
DOI: 10.1080/07328319708006225
To link to this article: http://dx.doi.org/10.1080/07328319708006225
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