An efficient multigram synthesis of monomers for the preparation of novel oligonucleotides containing isosteric non-phosphorous backbones

Article abstract of DOI:10.1080/07328319708006242

The facile preparation of two novel classes of nucleoside analogs for the inclusion as dimeric non-phosphorous containing subunits in chime fie backbones has been accomplished. The concise preparation of 3'- formylnucleosides and 5'-O-(N-methylhydroxylamino)-nucleosides is reported.

Full text of DOI:10.1080/07328319708006242

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Nucleosides and Nucleotides
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An Efficient Multigram Synthesis of
Monomers for the Preparation of Novel
Oligonucleotides Containing Isosteric
Non-Phosphorous Backbones
Stuart Dimock a , Balkrishen Bhat a , Didier Peoc'h a , Yogesh S.
Sanghvi a & Eric E. Swayze a
a Isis Pharmaceuticals, 2292 Faraday Ave., Carlsbad, CA, 92008
Published online: 16 Aug 2006.
To cite this article: Stuart Dimock , Balkrishen Bhat , Didier Peoc'h , Yogesh S. Sanghvi & Eric
E. Swayze (1997) An Efficient Multigram Synthesis of Monomers for the Preparation of Novel
Oligonucleotides Containing Isosteric Non-Phosphorous Backbones, Nucleosides and Nucleotides,
16:7-9, 1629-1632, DOI: 10.1080/07328319708006242
To link to this article: http://dx.doi.org/10.1080/07328319708006242
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