Chemoselective O-methylation of phenols under non-aqueous condition

DOI: 10.1016/S0040-4039(98)00885-5

Source and publish data:

Tetrahedron Letters p. 4883 - 4886 (1998)

Update date:2022-07-30

Topics:

Authors:

Basak, Anindita

Nayak, Mrinal K.

Chakraborti, Asit K.

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Article abstract of DOI:10.1016/S0040-4039(98)00885-5

Chemoselective O-methylation of substituted phenols takes place in dry. tetrahydrofuran (THF) in the presence of LiOH.H₂O and dimethylsulfate (DMS). Quantitative methyl transfer from DMS preserves the atom economy.

Full text of DOI:10.1016/S0040-4039(98)00885-5

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