Synthesis of the central heterocyclic skeleton of an antibiotic, A10255

DOI: 10.1246/cl.1997.1203

Source and publish data:

Chemistry Letters p. 1203 - 1204 (1997)

Update date:2022-07-30

Topics:

Authors:

Umemura, Kazuyuki

Ikeda, Shin

Yoshimura, Juji

Okumura, Kazuo

Saito, Hiroyuki

Shin, Chung-Gi

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Article abstract of DOI:10.1246/cl.1997.1203

The central heterocyclic skeleton (13) of an antibiotic, A10255, was synthesized by stepwise introduction of two groups into the 2,6-positions of 3-{(4-ethoxycarbonyl)-2-thiazolyl}-pyridine, via 17 steps in 4.8% total yield.

Full text of DOI:10.1246/cl.1997.1203

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