Enantioselective synthesis of the C1-C28 portion of the cytotoxic natural product, amphidinolide B1

DOI: 10.1016/S0040-4039(97)10103-4

Source and publish data:

Tetrahedron Letters p. 7909 - 7910 (1997)

Update date:2022-08-03

Topics:

Authors:

Lee, Duck-Hyung

Lee, Suk-Won

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)10103-4

The C1-C28 portion of the cytotoxic natural product, amphidinolide B1 (1a), was synthesized enantioselectively using as key steps Evans chiral oxazolidinone chemistry, Sharpless asymetric epoxidation, and the orthoester Claisen rearrangement. The overall

Full text of DOI:10.1016/S0040-4039(97)10103-4

Products guided by the article

Product name:(4S,5R)-3-((R)-4-Bromo-2-methyl-pent-4-enoyl)-4-methyl-5-phenyl-oxazolidin-2-one

Cas No:199612-89-0

R&D Labs maybe for 199612-89-0

Zhejiang kehong chemical co., ltd

Contact:0086-575-85522000

Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Sarchem Laboratories, Inc.

Contact:732.938.2777

Address:5012 Industrial Road Farmingdale, NJ 07727
Zhejiang Genebest Pharmaceutical Co.,Ltd.

Contact:0086-571-63532866

Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China

Relevant to this article

A 1,6-ring closure mechanism for (+)-δ-cadinene synthase?

Doi:10.1021/ja211820p
(2012)
Spontaneous dimerization of 2-(4-methylphenylamino)thiophene

Doi:10.1007/BF02253121
(1997)
Nucleophilic phosphanylation of fluoroaromatic compounds with carboxyl, carboxymethyl, and aminomethyl functionalities - An efficient synthetic route to amphiphilic arylphosphanes

Doi:10.1002/(SICI)1099-0682(199801)1998:1<73::AID-EJIC73>3.0.CO;2-M
(1998)
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): Implications for the binding mode

Doi:10.1016/j.bmc.2005.05.013
(2005)
Total synthesis of analogs of topostin B, A DNA topoisomerase I inhibitor. Part 3: Improved synthesis of topostin B-1 analogs

Doi:10.1016/S0040-4020(97)10315-5
(1998)
Structurally simplified zaragozic acid (squalestatin): Stereoselective preparation of a 3,4-unsubstituted derivative

Doi:10.1016/S0040-4039(97)10407-5
(1997)

Article Doi