Bioorganic and Medicinal Chemistry Letters p. 2753 - 2758 (1997)
Update date:2022-07-30
Topics:
Kim, Oak K.
Hudyma, Thomas W.
Matiskella, John D.
Ueda, Yasutsugu
Bronson, Joanne J.
Mansuri, Muzammil M.
A series of cephalosporins bearing C-3 quaternary ammonium groups were prepared and evaluated for their anti-MRSA activity. They exhibit good to excellent in vitro activity (MICs= 1-8 μg/mL) against MRSA.
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