Nonclassical 5-substituted tetrahydroquinazolines as potential inhibitors of thymidylate synthase

DOI: 10.1002/jhet.5570340605

Source and publish data:

Journal of Heterocyclic Chemistry p. 1669 - 1676 (1997)

Update date:2022-08-05

Topics:

Authors:

Gangjee, Aleem

Vasudevan, Anil

Kisliuk, Roy L.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570340605

Classical inhibitors of thymidylate synthase such as N¹⁰-propargyl- 5,8-dideazafolic acid (1), N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6- ylmethyl)-N-methylamino]-2-thenoyl)-L-glutamic acid (ZD1694, 2) and N-[2- amino-4-oxo-3,4-dihydro(py

Full text of DOI:10.1002/jhet.5570340605

Products guided by the article

Product name:4-Methyl-2-oxo-6-phenylsulfanyl-cyclohexanecarboxylic acid ethyl ester

Cas No:202720-93-2

R&D Labs maybe for 202720-93-2

Tangshan Wisdom Trading Co.,Ltd

Contact:86 315 2222979

Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
FREEBARQUE DEVELOPMENT GROUP LIMITED

Contact:+86(0)10-5109 5335 or 5109 5345

Address:Room602,Block1-B,LINGDI OFFICE,NO.13 BEIYUAN ROAD
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
puyang hongda shengdao new material co.,ltd.

Contact:+86-393- 4896278

Address:No.29 East Zhongyuan Road
Shanghai Micro-mega Industry Co., Ltd.

Contact:0086-21-34628682;57153848

Address:Rm413,No.413,West Meilong Road, Minhang District,Shanghai P R China

Relevant to this article

A new magnesium-catalyzed doubly diastereoselective anti-aldol reaction leads to a highly efficient process for the total synthesis of lactacystin in quantity

Doi:10.1021/ja973444c
(1998)
ALKALOIDS OF HEIMIA MONTANA

Doi:10.1016/0031-9422(90)80146-8
(1990)
Synthesis and characterization of a novel ^99mTc analogue of ?i-: M IBG showing affinity for nor-epinephrine transport positive tumors

Doi:10.1039/c6ra11217j
(2016)
The Cleavage of a C-C Bond in Cyclobutylanilines by Visible-Light Photoredox Catalysis: Development of a [4+2] Annulation Method

Doi:10.1002/anie.201504076
(2015)
New efficient methods for the synthesis and in-situ preparation of ruthenium(II) complexes of atropisomeric diphosphines and their application in asymmetric catalytic hydrogenations

Doi:10.1016/S0957-4166(00)82157-6
(1991)
Doi:10.1016/0040-4020(68)88168-2
(1968)

Article Doi