Cyclization of 5-alkynones with chromium alkylidene equivalents generated: In situ from gem -dichromiomethanes

Article abstract of DOI:10.1039/d0cc03986a

A rare example of cyclization with 5-alkynones, which possess non-polar alkynyl and less electrophilic polar keto carbonyl groups, was demonstrated. The key to promoting carbene/alkyne metathesis followed by alkylidenation with pendant CO double bonds was the Schrock-type nucleophilic reactivity of the generated chromium carbene equivalents from readily available diiodomethanes and CrCl2 by simple heating.