Synthesis of 2'-deoxynucleoside 5'-methylenebis-(phosphonate)s using 2- (4-nitrophenyl)ethyl mthylene-bis(phosphonate) as the phosphonylating agent

DOI: 10.1080/07328319808004723

Source and publish data:

Nucleosides and Nucleotides p. 1857 - 1860 (1998)

Update date:2022-08-05

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Authors:

Lesiak, Krystyna

Watanabe, Kyoichi A.

Pankiewicz, Krzysztof W.

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Article abstract of DOI:10.1080/07328319808004723

2-(4-Nitrophenylethyl) methylenebis(phosphonate) (1) has been prepared by reaction of 2-(4-nitrophenyl)ethyl alcohol with methylenebis(phosphonyl) tetrachloride. Compound 1 was treated with diisopropylcarbodiimide (DIC) to give bicyclic intermediate 2, wh

Full text of DOI:10.1080/07328319808004723

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