Journal of Medicinal Chemistry p. 436 - 438 (1976)
Update date:2022-08-03
Topics:
Aeberli
Gogerty
Houlihan
Iorio
A series of aryl bicycle analogs of succinimide and glutarimide was prepared and evaluated for CNS depressant activity. The 8a aryl 3,4,6,7,8,8a hexahydro 2H pyrrolo[2,1 b] [1,3]oxazin 6 ones possessed the best overall spectrum of activity relative to the standard agents glutethimide and phenobarbital.
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