First total synthesis of 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines

DOI: 10.1016/S0040-4039(97)10737-7

Source and publish data:

Tetrahedron Letters p. 1231 - 1232 (1998)

Update date:2022-08-04

Topics:

Authors:

Martinez, Elena

Estevez, Juan C.

Estevez, Ramon J.

Villaverde, M. Carmen

Castedo, Luis

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)10737-7

Here we describe the first total synthesis of 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines (7) from N-acyl-o-styrylphenylethylamines 3. It proceeds by the Bischler-Napieralski reaction to form the isoquinoline unit and photocyclization of the resulting 5-styrylisoquinolines.

Full text of DOI:10.1016/S0040-4039(97)10737-7

Products guided by the article

Product name:1-Methyl-5-((E)-styryl)-1,2,3,4-tetrahydro-isoquinoline

Cas No:204002-22-2

R&D Labs maybe for 204002-22-2

Nanjing Chemlin Chemical Co., Ltd.

website:http://www.echemlin.cn

Contact:+86-25-83697070

Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Anhui Sholon New Material Technology Co., Ltd.

website:http://www.sholonchem.com

Contact:+86-550-5261666

Address:4/F Block B, Beijing Chemical Building.No.520 Tianrun Road ,Science & Education Town Wujin District, Changzhou City Jiangsu Province
Taizhou Huading Chemical Co.,Ltd(expird)

Contact:+86-576-88583898

Address:Economic&Technology development zone,Taizhou City,Zhejiang Province,China
Shanghai Korey Pharm Co.,Ltd.(expird)

Contact:021-61840961 021-61840962

Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
Hangzhou TJM Chemical Trade Co., Ltd

Contact:86-571-88223276 86-13388481653

Address:2221#,Boyuexuan,1860# Binsheng Road,Binjiang District, Hangzhou CityZhejiang Province, 310051, P. R. China

Relevant to this article

A diastereodivergent synthetic strategy for the syntheses of communesin F and perophoramidine

Doi:10.1021/ol5013263
(2014)
Pectenotoxin-2 synthetic studies. 3. Assessment of the capacity for stereocontrolled cyclization to form the entire C1-C26 subunit based upon the double bond geometry across C15-C16

Doi:10.1021/jo062513f
(2007)
Doi:10.1021/jo01038a013
(1963)
USING THE COMPARISON OF STERIC VERSUS ELECTRONIC EFFECTS TO INFER MECHANISTIC INFORMATION IN STEPWISE ELECTROPHILIC ADDITION REACTIONS INVOLVING THREE-MEMBERED CYCLIC INTERMEDIATES

Doi:10.1016/S0040-4039(00)82306-0
(1988)
ON THE FACILE DEHYDROHALOGENATION OF AMINO ACID DERIVED CHLOROMETHYL KETONES.

Doi:10.1016/S0040-4039(01)81363-0
(1984)
SYNTHESIS OF 6S,7S-ANHYDRO-SERRICORNINE.

Doi:10.1016/S0040-4039(00)87646-7
(1982)

Article Doi