Tetrahedron Letters p. 1231 - 1232 (1998)
Update date:2022-08-04
Topics:
Martinez, Elena
Estevez, Juan C.
Estevez, Ramon J.
Villaverde, M. Carmen
Castedo, Luis
Here we describe the first total synthesis of 1,2,3,4-tetrahydronaphtho[2,1-f]isoquinolines (7) from N-acyl-o-styrylphenylethylamines 3. It proceeds by the Bischler-Napieralski reaction to form the isoquinoline unit and photocyclization of the resulting 5-styrylisoquinolines.
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