Synthesis of LIAZAL, a retinoic acid metabolism blocking agent (RAMBA) with potential clinical applications in oncology and dermatology.

DOI: 10.1016/S0960-894X(98)00004-3

Source and publish data:

Bioorganic and medicinal chemistry letters p. 267 - 272 (1998)

Update date:2022-08-04

Topics:

Authors:

Freyne Freyne

Raeymaekers

Venet Venet

Sanz Sanz

Wouters Wouters

De Coster

Wauwe Wauwe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00004-3

The synthesis of LIAZAL (compound 9, R085246) is described. LIAZAL inhibits all-trans-retinoic acid metabolism and thereby exerts retinoid-like effects in vivo.

Full text of DOI:10.1016/S0960-894X(98)00004-3

Products guided by the article

Product name:(4-amino-3-nitrophenyl)-3-chlorophenylmethanol

Cas No:204255-40-3

R&D Labs maybe for 204255-40-3

Yicheng Goto Pharmaceuticals Co.,Ltd.

Contact:+86 710 3423122

Address:5th Floor,East Gate of Building #2,Servo-Industrial Park,1st Qilin Road,Xiangyang,Hubei,China
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
Shanghai FWD Chemicals ltd

website:http://www.fwdchem.com

Contact:86-21-54450828

Address:Room 802,Lotus Tower ,159 Tianzhou Road,Xuhui District,Shanghai
ZHEJIANG JIANYE CHEMICAL CO.,LTD.

Contact:86-571-64149273,64149234

Address:No. 48, Fuxi Road, Meicheng Town
QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071

Relevant to this article

Doi:10.1021/ja00784a041
(1973)
Nonenzymatic, self-elimination degradation mechanism of glutathione

Doi:10.1002/cbdv.200800277
(2009)
2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Doi:10.1021/jm00371a006
(1984)
A conformational study of beta-phenethanolamine receptor sites. 3. Synthesis of the 3-isopropylamino-2-phenyl-trans-2-decalols.

Doi:10.1021/jm00283a007
(1971)
Doi:10.1039/jr9550002657
(1955)
Cyclic alpha, beta-unsaturated ketones related to ethacrynic acid.

Doi:10.1002/jps.2600570503
(1968)

Article Doi