Bioorganic and Medicinal Chemistry Letters p. 133 - 138 (1998)
Update date:2022-08-03
Topics:
Drysdale, Martin J.
Reinhard, John F.
A series of 2-amino-S-aryl cysteine S,S-dioxides have been synthesised and shown to inhibit kynureninase an important enzyme in the biosynthesis of the known excitotoxic moiety quinolinic acid. The most potent of these, 2-amino-5-methyl-S-phenyl cysteine S,S-dioxide 6d, inhibits interferon-γ induced synthesis of quinolinic acid in human macrophages.
View MoreContact:0543-3317184
Address:No.1401, Unit 1, Global building, Binzhou city, shandong PRC.
Weifang Jahwa Chemical Co.,Ltd
Contact:0086-536-8897731,8897730
Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
SuZhou Bichal Biological Technology CO.,LTD
Contact:+86-512-68051130
Address:NO.32 huoju road HI-TECH Industrial development zone SuZhou China
NINGBO YINLIANG FOREIGN TRADE CO., LTD.
Contact:+86-574-87834016 / 87898057
Address:23F NO.666JINYU ROAD,YINGZHOU DISTRICT,NINGBO.CHINA
Kunshan Yalong Trading Co,.Ltd
Contact:86-512-57621185
Address:805-807 Room Hongqiao Mansion ,1088 West Qianjin Road, Kunshan, Jiangsu,China
Doi:10.1016/S0040-4039(97)01716-4
(1997)Doi:10.1246/cl.1985.427
(1985)Doi:10.1021/jo01027a535
(1964)Doi:10.1021/ja00759a052
(1972)Doi:10.1080/10426509608029649
(1996)Doi:10.1021/ja972981u
(1998)