Journal of labelled compounds and radiopharmaceuticals p. 319 - 327 (1998)
Update date:2022-08-03
Topics:
Hamill, Terence G.
Brenner, Nancy J.
Eng, Wai-Si
Burns, H. Donald
The synthesis of three tritiated reverse transcriptase inhibitors is described herein. These compounds contained the benzoxazole ring linked to a 2-pyridinone ring by an aminomethylene group. The tritiated compounds were synthesized by hydrogenolysis of bromobenzoxazole precursors. The final tritiated compounds had specific activities ranging from 3-10 Cl/mmol.
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