Dual CCK-A and CCK-B receptor antagonists (II). Preparation and structure activity relationships of 5-alkyl-9-methyl-1,4-benzodiazepines and discovery of FR208419

DOI: 10.1248/cpb.48.1

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1 - 15 (2000)

Update date:2022-09-26

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Authors:

Tabuchi, Seiichiro

Ito, Harunobu

Sogabe, Hajime

Kuno, Masako

Kinoshita, Takayoshi

Katumi, Ikuyo

Yamamoto, Naoko

Mitsui, Hitoshi

Satoh, Yoshinari

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Article abstract of DOI:10.1248/cpb.48.1

In our continuing research for dual CCK-A and -B antagonists, according to our hypothesis that dual CCKA and -B antagonists should be more efficacious than selective CCK-A antagonists for the treatment of pancreatitis, we have prepared various 5-alkyl-9-m

Full text of DOI:10.1248/cpb.48.1

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