Tetrahedron Letters p. 2349 - 2352 (1998)
Update date:2022-07-30
Topics:
Murakami, Nobutoshi
Wang, Weiqi
Aoki, Masashi
Tsutsui, Yasuhiro
Sugimoto, Masanori
Kobayashi, Motomasa
A first total synthesis of callystatin A (1), a potent cytotoxic polyketide from the marine sponge Callyspongia truncata, has been achieved by use of an E-selective Wittig olefination and asymmetric Evans aldol condensation as the key reactions. Thus, the
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Doi:10.1016/0040-4039(80)80192-4
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(1998)
