Total synthesis of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata

DOI: 10.1016/S0040-4039(98)00151-8

Source and publish data:

Tetrahedron Letters p. 2349 - 2352 (1998)

Update date:2022-07-30

Topics:

Authors:

Murakami, Nobutoshi

Wang, Weiqi

Aoki, Masashi

Tsutsui, Yasuhiro

Sugimoto, Masanori

Kobayashi, Motomasa

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Article abstract of DOI:10.1016/S0040-4039(98)00151-8

A first total synthesis of callystatin A (1), a potent cytotoxic polyketide from the marine sponge Callyspongia truncata, has been achieved by use of an E-selective Wittig olefination and asymmetric Evans aldol condensation as the key reactions. Thus, the

Full text of DOI:10.1016/S0040-4039(98)00151-8

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