Non-peptide fibrinogen receptor antagonists. 2. The synthesis of [3H]L- 738,167

DOI: 10.1002/(SICI)1099-1344(199804)41:4<273::AID-JLCR76>3.0.CO;2-1

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 273 - 277 (1998)

Update date:2022-08-03

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Authors:

Hamill, Terence G.

Askew, Ben C.

Hartman, George D.

Claremon, David A.

McIntyre, Charles J.

Burns, H. Donald

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Article abstract of DOI:10.1002/(SICI)1099-1344(199804)41:4<273::AID-JLCR76>3.0.CO;2-1

The synthesis of [²H]L-738,167, an orally active fibrinogen receptor antagonist, is described. A precursor containing the 2-bromotolyl moiety was synthesized, and a reductive debromination reaction using tritium gas and Pearlman's catalyst gave

Full text of DOI:10.1002/(SICI)1099-1344(199804)41:4<273::AID-JLCR76>3.0.CO;2-1

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