Stereoselective synthesis of 6,5-bicyclic reverse-turn peptidomimetics

DOI: 10.1016/S0040-4020(98)00207-5

Source and publish data:

Tetrahedron p. 5325 - 5336 (1998)

Update date:2022-08-03

Topics:

Authors:

Colombo, Lino

Di Giacomo, Marcello

Brusotti, Gloria

Sardone, Nicola

Angiolini, Mauro

Belvisi, Laura

Maffioli, Sonia

Manzoni, Leonardo

Scolastico, Carlo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)00207-5

A flexible stereoselective synthetic scheme was developed to prepare 6,5-fused bicyclic lactams, that molecular mechanics calculations revealed to have a potential as reverse-turn mimetics. The convergence of the synthetic sequence was achieved by attachm

Full text of DOI:10.1016/S0040-4020(98)00207-5

Products guided by the article

Product name:(2S,5S)-1-[(2S,R)-methoxycarbonyl-3-phenyl-propionyl]-5-(2-hydroxyethyl)pyrrolidine-2-carboxylic acid tert-butyl ester

Cas No:208455-15-6

R&D Labs maybe for 208455-15-6

Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
JinTan Pingsheng Chemical Co.,Ltd

Contact:+86-519-82828200

Address:NO.11Danfengxilu Road,Jintan City,Jiangsu,China
TLS PHARMACEUTICAL CO.,LTD

Contact:0833-5590788/5590338/5590055

Address:Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark
Shanggao Ruiya Fine Chemicals Co., Ltd

Contact:+86-795-2592103

Address:Xingguang Nanlu,Shanggao County Industry Park
Hangzhou Donglou Bio-nutrient Co., Ltd.

Contact:+86-571-82225795,13967112289

Address:Louta Town, Xiaoshan,Hangzhou,Zhejiang

Relevant to this article

Doi:10.1016/S0022-328X(00)98043-4
(1976)
Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery

Doi:10.1002/chem.201702362
(2017)
A stereoselective one-pot synthesis of perhydro-7a-hydroxy-7- phenylthiofurano[3,2-b]pyran via an acid-catalysed deprotection/double cyclisation/rearrangement sequence

Doi:10.1016/S0040-4039(98)00560-7
(1998)
5-Oxazolones. Part V. Reaction of 4-alkylidene-5(4h)-oxazolones with ethyl 3-oxo-4-triphenylphosphoranylidene-butyrate

Doi:10.1016/S0040-4020(01)81003-6
(1991)
Ring Opening versus Phenyl-Phosphorous Bond Clevage in incorporating a Phosphole into Triosmium Clusters

Doi:10.1039/DT9910003381
(1991)
Assay and inhibition of diacylglycerol lipase activity

Doi:10.1016/j.bmcl.2012.05.101
(2012)

Article Doi