Tetrahedron Letters p. 3421 - 3424 (1998)
Update date:2022-09-26
Topics:
Harmata, Michael
Kahraman, Mehmet
Treatment of a THF solution of (E)-3 with n-BuLl followed by quenching with an electrophile generally results in regioselective alkylation alpha to the sulfone with the alkene possessing (E) stereochemistry in the major product. High selectivity for the (E) alkylation product can be achieved in the presence of small amounts of HMPA. When those (E) alkylation products possessing a diene moiety in the side chain are treated with Lewis acids, 4+3 cycloaddition products are formed in good to excellent yields.
View MoreContact:+86-571-86217390
Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
Jiangxi Hessence Chemicals Co., Ltd.
Contact:+86 796 3511924
Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Xi'an Costrong Pharmaceutical Co., Ltd.
Contact:029- 68576496
Address:Room 2004,Shuibao Building,No.190,South Erhuan Rd, Yanta District,Xi'an,Shaan Xi,China
guide(suzhou) fine materials co. ltd
Contact:0512-80972173
Address:21st Building, No.369 Lushan Rd, New District Suzhou China 215129
Contact:86-21-50966856
Address:Building 5,300 Chuanzhan Road,Pudong New District,Shanghai
Doi:10.3184/174751912X13518648205073
(2012)Doi:10.1021/jm00310a046
(1968)Doi:10.1016/S0008-6215(97)10084-2
(1998)Doi:10.1016/S0020-1693(00)87298-9
(1982)Doi:10.1038/sj.bjp.0705233
(2003)Doi:10.1016/S0040-4039(00)94797-X
(1985)
