Bioorganic and Medicinal Chemistry Letters p. 2299 - 2302 (1997)
Update date:2022-08-03
Topics:
Broadhurst
Brown
Lawton
Ballantyne
Borkakoti
Bottomley
Cooper
Eatherton
Kilford
Malsher
Nixon
Lewis
Sutton
Johnson
A novel series of MMP inhibitors has been identified. The compounds are potent selective inhibitors of collagenase with good solubility and oral bioavailability. One compound, designated Ro32-3555, has been selected for development as a cartilage protective agent for use in the treatment of rheumatoid- and osteoarthritis.
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Doi:10.1248/cpb.47.146
(1999)Doi:10.1080/07328309908543989
(1999)Doi:10.1246/cl.1977.7
(1977)Doi:10.1007/BF00938236
(1969)Doi:10.1016/j.dyepig.2019.02.051
(2019)Doi:10.1039/a807567k
(1999)
