
Bioorganic and Medicinal Chemistry Letters p. 3251 - 3256 (1998)
Update date:2022-07-30
Topics:
Sheppard, George S.
Florjancic, Alan S.
Giesler, Jamie R.
Xu, Lianhong
Guo, Yan
Davidsen, Steven K.
Marcotte, Patrick A.
Elmore, Ildiko
Albert, Daniel H.
Magoc, Terrance J.
Bouska, Jennifer J.
Goodfellow, Carole L.
Morgan, Douglas W.
Summers, James B.
A series of succinyl hydroxamate MMP inhibitors were prepared incorporating an aryl amino ketone moiety in place of the more typical C- terminal amino acid amides. Compounds of the C-terminal ketone series displayed potent inhibition of MMPs. Several comp
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Doi:10.1016/S0040-4020(98)00346-9
(1998)Doi:10.1016/S0008-6215(98)00066-4
(1998)Doi:10.1021/jo980450y
(1998)Doi:10.1016/S0022-328X(98)00564-6
(1998)Doi:10.1016/S0040-4020(98)01044-8
(1999)Doi:10.1016/S0040-4039(98)01243-X
(1998)