Rapid synthesis of a 5'-fluorinated oligodeoxy-nucleotide: A model antisense probe for use in imaging with positron emission tomography (PET)

DOI: 10.1016/S0960-894X(98)00239-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1317 - 1320 (1998)

Update date:2022-08-05

Topics:

Authors:

Pan, Dongfeng

Gambhir, Sanjiv S.

Toyokuni, Tatsushi

Iyer, Meera R.

Acharya, Naveen

Phelps, Michael E.

Barrio, Jorge R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00239-X

5'-Deoxy-5'-fluoro-O⁴-methylthymidine was synthesized by the reaction of the corresponding 5'-O-tosylate with KF in the presence of Kryptofix [222] and coupled to a 5'-phosphoramidite-activated CPG-bound oligodeoxynucleotide. The sequence of re

Full text of DOI:10.1016/S0960-894X(98)00239-X

Products guided by the article

Product name:Acetic acid (2R,3S,5R)-5-(4-methoxy-5-methyl-2-oxo-2H-pyrimidin-1-yl)-2-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester

Cas No:210910-68-2

R&D Labs maybe for 210910-68-2

Tosta Enterprise Co., Ltd.

Contact:+86-134-5286-9121

Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Suzhou Wedo Chemicals Co., Ltd.

Contact:86 512 58100425

Address:Zonger Road, DongSha Industry Park , Zhangjiagang, Jiangsu, China
Beijing Century Richap Chemistry Co.,Ltd

Contact:+86- 010-64455497

Address:Guannan County, Lianyungang City, Jiangsu Province, China
Shanghai FWD Chemicals ltd

website:http://www.fwdchem.com

Contact:86-21-54450828

Address:Room 802,Lotus Tower ,159 Tianzhou Road,Xuhui District,Shanghai
Henan Sinotech Import&Export Corporation

website:http://www.hasinotech.com

Contact:86-371-86181678

Address:No. 260, Dongming Road,Jinshui District

Relevant to this article

Visible Light Initiated Photosensitized Electron Transfer Cyclizations of Aldehydes and Ketones to Tethered αβ-Unsaturated Esters: Stereoselective Synthesis of Optically Pure C-Furanosides

Doi:10.1021/jo9702812
(1997)
Doi:10.1007/BF00601126
()
Doi:10.1002/jhet.5570370639
(1957)
Heterocycles LXXVIII. Electrophilic substitution of 2′-phenyl-4R-2,4′-bisthiazoles

Doi:10.1007/pl00013474
(1998)
Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP)

Doi:10.1016/S0968-0896(98)00029-7
(1998)
Mechanism of the Reaction of Nitriles with Alkaline Hydrogen Peroxide. Reactivity of Peroxycarboximidic Acid and Application to Superoxide Ion Reaction

Doi:10.1246/bcsj.54.793
(1981)

Article Doi