Rapid synthesis of a 5'-fluorinated oligodeoxy-nucleotide: A model antisense probe for use in imaging with positron emission tomography (PET)

DOI: 10.1016/S0960-894X(98)00239-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1317 - 1320 (1998)

Update date:2022-08-05

Topics:

Authors:

Pan, Dongfeng

Gambhir, Sanjiv S.

Toyokuni, Tatsushi

Iyer, Meera R.

Acharya, Naveen

Phelps, Michael E.

Barrio, Jorge R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00239-X

5'-Deoxy-5'-fluoro-O⁴-methylthymidine was synthesized by the reaction of the corresponding 5'-O-tosylate with KF in the presence of Kryptofix [222] and coupled to a 5'-phosphoramidite-activated CPG-bound oligodeoxynucleotide. The sequence of re

Full text of DOI:10.1016/S0960-894X(98)00239-X

Products guided by the article

Product name:Acetic acid (2R,3S,5R)-5-(4-methoxy-5-methyl-2-oxo-2H-pyrimidin-1-yl)-2-(toluene-4-sulfonyloxymethyl)-tetrahydro-furan-3-yl ester

Cas No:210910-68-2

R&D Labs maybe for 210910-68-2

Nanyang Tianhua pharmaceutical Co.,Ltd.

Contact:+8618639816203

Address:Longsheng Industrial Park
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
Anqing World Chemical Co., Ltd.

Contact:+86-556-5800026

Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
Qingdao XinYongAn Chemicals Co., Ltd

Contact:+86-532-81107967

Address:Chengyang dual-port industrial park by the sea，Qingdao
Yancheng KangdiSen Pharmaceutical Co., Ltd.

Contact:18951519681

Address:Yancheng City Funing County Yilin town Huaihai Road, No. 46

Relevant to this article

Visible Light Initiated Photosensitized Electron Transfer Cyclizations of Aldehydes and Ketones to Tethered αβ-Unsaturated Esters: Stereoselective Synthesis of Optically Pure C-Furanosides

Doi:10.1021/jo9702812
(1997)
Doi:10.1007/BF00601126
()
Doi:10.1002/jhet.5570370639
(1957)
Heterocycles LXXVIII. Electrophilic substitution of 2′-phenyl-4R-2,4′-bisthiazoles

Doi:10.1007/pl00013474
(1998)
Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP)

Doi:10.1016/S0968-0896(98)00029-7
(1998)
Mechanism of the Reaction of Nitriles with Alkaline Hydrogen Peroxide. Reactivity of Peroxycarboximidic Acid and Application to Superoxide Ion Reaction

Doi:10.1246/bcsj.54.793
(1981)

Article Doi