Journal of Heterocyclic Chemistry p. 1139 - 1146 (1997)
Update date:2022-09-26
Topics:
Lomenzo, Stacey A.
Bradley, Amy L.
Zhu, Naijue
Klein, Cheryl L.
Trudell, Mark L.
A new synthetic approach for the regiospecific alkylation of the 6-position of the tropane ring system has been developed. Alkylation, desulfonylation and deprotection of tropanes 5 and 12 furnished a series of 6-endo-alkyltropan-2-one derivatives 8a-e, 1
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