Tetrahedron Letters p. 5313 - 5316 (1998)
Update date:2022-08-03
Topics:
Dutton, Fred E.
Byung H, Lee
Conformationally restricted analogs of the anthelmintic cyclodepsipeptide PF1022A 1 were prepared by fusing a seven-membered lactam ring onto the macrocycle. Following the preparation of cyclodepsipeptide (CDP) 2 by classical chemical methods, CDPs 2 and 3 were synthesized using solid phase methodology involving cyclization-cleavage from an oxime resin.
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Doi:10.1002/jhet.5570360142
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