Studies on disease-modifying antirheumatic drugs. II. Synthesis and activity of the metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy- 2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (TAK-603)

DOI: 10.1248/cpb.46.1130

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1130 - 1134 (1998)

Update date:2022-08-03

Topics:

Authors:

Baba, Atsuo

Makino, Haruhiko

Ohta, Yoshikazu

Sohda, Takashi

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Article abstract of DOI:10.1248/cpb.46.1130

The metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2- (1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (1, TAK-603), which is under clinical evaluation as a new type of disease-modifying antirheumatic drug (DMARD), were prepared to confirm th

Full text of DOI:10.1248/cpb.46.1130

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