Studies on disease-modifying antirheumatic drugs. II. Synthesis and activity of the metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy- 2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (TAK-603)

DOI: 10.1248/cpb.46.1130

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1130 - 1134 (1998)

Update date:2022-08-03

Topics:

Authors:

Baba, Atsuo

Makino, Haruhiko

Ohta, Yoshikazu

Sohda, Takashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.46.1130

The metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2- (1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (1, TAK-603), which is under clinical evaluation as a new type of disease-modifying antirheumatic drug (DMARD), were prepared to confirm th

Full text of DOI:10.1248/cpb.46.1130

NII-Electronic Library Service

Products guided by the article

Product name:3-(3,4-Dimethoxy-phenyl)-5-isopropoxy-6-methoxy-1H-indole-2-carboxylic acid methyl ester

Cas No:212490-31-8

R&D Labs maybe for 212490-31-8

Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone
QUZHOU ZIO I/E CO.;LTD

Contact:13357117572

Address:No.149 Shiji dadao Road.
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Shandong LuZhou Amino Acid Co., Ltd

Contact:86-539-2218025

Address:yishui economic and technical development zone zhenxing south road
suzhou BetterBioChem Co., Ltd.

website:http://www.betterbiochem.com

Contact:+86-18013506594

Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China

Relevant to this article

Galactose-decorated light-responsive hydrogelator precursors for selectively killing cancer cells

Doi:10.1039/c6cc05707a
(2016)
Chromium(III) complexes bearing N,N-chelate ligands as ethene polymerization catalysts

Doi:10.1039/a802797h
(1998)
Thermoreversible gelation of organic liquids by arylcyclohexanol derivatives: Synthesis and characterisation of the gels

Doi:10.1039/a801922c
(1998)
Doi:10.1021/jo01046a525
(1963)
The catalytic olefination reaction of aldehydes and ketones with CBr ₃CF₃

Doi:10.1016/j.jfluchem.2005.03.020
(2005)
Heck vinylations using vinyl sulfide, vinyl sulfoxide, vinyl sulfone, or vinyl sulfonate derivatives and aryl bromides catalyzed by a palladium complex derived from a tetraphosphine

Doi:10.1055/s-2006-950244
(2006)

Article Doi