Incorporation of serinol derived acyclic nucleoside analogues into oligonucleotides: Influence on duplex and triplex formation

DOI: 10.1016/S0040-4039(98)01268-4

Source and publish data:

Tetrahedron Letters p. 6167 - 6170 (1998)

Update date:2022-08-02

Topics:

Authors:

Benhida, Rachid

Devys, Michel

Fourrey, Jean-Louis

Lecubin, Florence

Sun, Jian-Sheng

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Article abstract of DOI:10.1016/S0040-4039(98)01268-4

Phosphoramidites 6a-c were readily prepared by an original route and used to incorporate serinol derived units I-III in oligonucleotides which, compared to their natural analogues, exhibited a decreased hybridization capacity for duplex and triplex format

Full text of DOI:10.1016/S0040-4039(98)01268-4

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