Synthesis of indolizidines (-)-195B, (-)-223AB and (-)-239AB: (2S,5R)- l-[(benzyloxy)carbonyl]-2-methoxycarbonyl-5-(4pentenyl)pyrrolidine as a versatile chiral building block

DOI: 10.1016/S0040-4020(98)00498-0

Source and publish data:

Tetrahedron p. 10457 - 10468 (1998)

Update date:2022-08-05

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Authors:

Celimene, Catherine

Dhimane, Hamid

Lhommet, Gerard

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Article abstract of DOI:10.1016/S0040-4020(98)00498-0

The total syntheses of three levogyre 3,5-disubstituted indolizidines, (-)-195B, (-)-223AB and (-)-239AB are described. The employed strategy is based on the utilization of the common enantiopure trans 2,5-disubstituted pyrrolidine 3, which is assembled b

Full text of DOI:10.1016/S0040-4020(98)00498-0

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Product name:(2R,5R)-1-[(Benzyloxy)carbonyl]-2-butyl-5-(4,5-epoxypentyl)pyrrolidine

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