H-phosphonate derivatives as novel peptide deformylase inhibitors

DOI: 10.1016/S0960-894X(98)00443-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2479 - 2482 (1998)

Update date:2022-08-04

Topics:

Authors:

Hu, Yun-Jin

Rajagopalan, P. T. Ravi

Pei, Dehua

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00443-0

Peptide deformylase catalyzes the removal of the N-terminal formyl group from nascent polypeptides during prokaryotic protein maturation and is essential for bacterial survival. Its absence from eukaryotic organisms makes it an attractive target for desig

Full text of DOI:10.1016/S0960-894X(98)00443-0

Products guided by the article

Product name:(S)-2-Hydroxy-hexanoic acid [(S)-3-methyl-1-(4-nitro-phenylcarbamoyl)-butyl]-amide

Cas No:216494-70-1

R&D Labs maybe for 216494-70-1

Tianjin Hedong Red Cliff Chemical Reagent Factory

Contact:+86-022-84780548

Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China
Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road
Ningxia Soochow Agrochemical Limited Company

Contact:(+86）0512 6320 8190

Address:wujiang
hangzhou verychem science and technology co.ltd

website:http://www.verypharm.com

Contact:+86-571-88162785; 88162786

Address:F1502, 753 Shenhua road, Hangzhou, China
Chengdu Boon Stream Chemical Industry Co.,Ltd.

Contact:+86-28-83156758

Address:No.859,Dongzikou Road,Jinniu District,Chengdu,Sichuan,P.R.China

Relevant to this article

Indane dimerization products obtained by treatment of N-acylindan-1-amines with ethyl polyphosphate (EPP)

Doi:10.1039/a804707c
(1998)
Acetic acid as a catalyst for the N-acylation of amines using esters as the acyl source

Doi:10.1039/c6cc09023k
(2017)
Doi:10.1021/jm00301a031
(1969)
Excited-state energy transfer and ground-state hole/electron hopping in p-phenylene-linked porphyrin dimers

Doi:10.1021/jp982729o
(1998)
The utility of N-methylimidazole and acetonitrile as solvents for the direct reaction of europium with alcohols including the first example of acetonitrile as a μ-η¹ : η¹-bridging ligand

Doi:10.1039/a805750h
(1998)
Photochemical Pinacol Rearrangements of Unsymmetrical Diols

Doi:10.1021/jo035439z
(2004)

Article Doi