H-phosphonate derivatives as novel peptide deformylase inhibitors

DOI: 10.1016/S0960-894X(98)00443-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2479 - 2482 (1998)

Update date:2022-08-04

Topics:

Authors:

Hu, Yun-Jin

Rajagopalan, P. T. Ravi

Pei, Dehua

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00443-0

Peptide deformylase catalyzes the removal of the N-terminal formyl group from nascent polypeptides during prokaryotic protein maturation and is essential for bacterial survival. Its absence from eukaryotic organisms makes it an attractive target for desig

Full text of DOI:10.1016/S0960-894X(98)00443-0

Products guided by the article

Product name:(S)-2-Hydroxy-hexanoic acid [(S)-3-methyl-1-(4-nitro-phenylcarbamoyl)-butyl]-amide

Cas No:216494-70-1

R&D Labs maybe for 216494-70-1

Zibo HaiDing chemical plant

Contact:13864437655

Address:Zibo city, shandong province Zhang Dian award and industrial park HaiDing chemical plant
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Xi'an HO-SHINE Bio-Technology Co., Ltd

Contact:+86 (29) 8248-5435/18292020086

Address:No.6 Shiyuan Road Xian City Shaanxi Province, 710048 China

Relevant to this article

Indane dimerization products obtained by treatment of N-acylindan-1-amines with ethyl polyphosphate (EPP)

Doi:10.1039/a804707c
(1998)
Acetic acid as a catalyst for the N-acylation of amines using esters as the acyl source

Doi:10.1039/c6cc09023k
(2017)
Doi:10.1021/jm00301a031
(1969)
Excited-state energy transfer and ground-state hole/electron hopping in p-phenylene-linked porphyrin dimers

Doi:10.1021/jp982729o
(1998)
The utility of N-methylimidazole and acetonitrile as solvents for the direct reaction of europium with alcohols including the first example of acetonitrile as a μ-η¹ : η¹-bridging ligand

Doi:10.1039/a805750h
(1998)
Photochemical Pinacol Rearrangements of Unsymmetrical Diols

Doi:10.1021/jo035439z
(2004)

Article Doi