Tetrahedron Letters p. 8081 - 8084 (1998)
Update date:2022-08-04
Topics:
Roussi, Fanny
Bonin, Martine
Chiaroni, Angele
Micouin, Laurent
Riche, Claude
Husson, Henri-Philippe
Starting with R-(-)-phenylglycinol, the synthesis of a new bicyclic hydrazinolactam 3 was realized on a multigram scale. The reaction scope of the corresponding enolate with various electrophiles has been studied. Good to excellent diastereoselectivities were obtained.
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