Implication and improvement of stereoselective methylenation of a chiral aldehyde related to total synthesis of the furaquinocins

DOI: 10.1016/S0040-4039(97)00746-6

Source and publish data:

Tetrahedron Letters p. 3755 - 3758 (1997)

Update date:2022-08-04

Topics:

Authors:

Saito, Takeshi

Suzuki, Takao

Takeuchi, Kazuhiro

Matsumoto, Takashi

Suzuki, Keisuke

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00746-6

In relation to the total synthesis of the furaquinocins, stereoselective methylenation of chiral aldehyde 5 is described. The diastereoselectivity of epoxides 6a/b is high when stabilized sulfur ylides are employed. A double stereo-differentiation phenomenon was observed for the aminosulfoxonium ylide 8: the selectivity with (S)-8 was 30:1, while 5:1 with (R)-8.

Full text of DOI:10.1016/S0040-4039(97)00746-6

Products guided by the article

Product name:(2R,3R)-9-Benzyloxy-6,7-dimethoxy-4-(2-methoxy-ethoxymethoxy)-2,3,8-trimethyl-3-(S)-oxiranyl-2,3-dihydro-naphtho[1,2-b]furan

Cas No:217486-38-9

R&D Labs maybe for 217486-38-9

jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Taizhou Chemedir Biopharm-tech Co., Ltd

Contact:+86 523 86200218

Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China
HUNAN OUYA BIOLOGICAL CO.,LTD

Contact:+8613400661290

Address:No 908,Kangwan Rd, Liuyang Economic
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China

Relevant to this article

Doi:10.1039/jr9600004347
(1960)
Toward the enantioselective total synthesis of lyngbyatoxin A: On the stereocontrolled introduction of the quaternary stereogenic centre

Doi:10.1016/S0040-4020(03)00822-6
(2003)
SYNTHESE D'ALKENYL ET DE CYCLOALKENYL POLYFLONES

Doi:10.1016/S0022-1139(00)81456-6
(1982)
Copper Triflate Mediated α-Monohalogenation of α-Diazo β-Ketosulfones with Ammonium Halides

Doi:10.1055/s-0036-1589479
(2017)
Doi:10.1016/S0040-4039(00)71337-2
(1976)
Synthesis and bio-evaluation of novel salicylic acid-oriented thiourea derivatives with potential applications in agriculture

Doi:10.2174/15701808113109990045
(2014)

Article Doi