
Tetrahedron Letters p. 8553 - 8556 (1998)
Update date:2022-08-05
Topics:
Cuevas, Juan C.
Martos, Jose L.
An enantiospecific synthesis of a monocyclic core of the antifungal sordarins and sordaricins has been achieved. This synthesis is based on the conversion of (+)-3,9-dibromocamphor into a 1,1,2,2,5-pentasubstituted cyclopentane bearing all the key functionalities present in these antifungals.
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Doi:10.1021/jm050879z
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