
Tetrahedron Letters p. 8349 - 8352 (1998)
Update date:2022-07-30
Topics:
Kaluza, Zbigniew
The Lewis acid promoted cyclisation of N-substituted-4- formyloxyazetidin-2-ones, easily available from 4-vinyloxyazetidin-2-one is described. The efficiency of the ring closure reaction, to give 1-oxacephams, depends on the oxygen protected-activated group and the Lewis acid.
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