Stereoselective synthesis and structural establishment of (25S)-24,24- difluoro-1α,25,26-trihydroxyvitamin D3, a major metabolite of 24,24- difluoro-1α,25-dihydroxyvitamin D3

DOI: 10.1016/S0040-4020(98)00949-1

Source and publish data:

Tetrahedron p. 14705 - 14724 (1998)

Update date:2022-09-26

Topics:

Authors:

Iwasaki, Hiroshi

Hosotani, Ryuzo

Miyamoto, Yoichi

Nakano, Yoshio

Yamamoto, Keiko

Yamada, Sachiko

Shinki, Toshimasa

Suda, Tatsuo

Yamaguchi, Kentaro

Konno, Katsuhiro

Takayama, Hiroaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)00949-1

(25S)-24,24-Difluoro-1α,25,26-trihydroxyvitamin D₃ (3a) and its (25R)- epimer (3b), either of which is expected to be a major metabolite of 24,24- difluoro-1α,25-dihydroxyvitamin D₃ (2), were synthesized. Asymmetric addition to β-ket

Full text of DOI:10.1016/S0040-4020(98)00949-1

Products guided by the article

Product name:(R)-6-{(1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-3,3-difluoro-1-((R)-toluene-4-sulfinyl)-heptan-2-one

Cas No:219123-54-3

R&D Labs maybe for 219123-54-3

Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road
Chinapeptides Co,. Ltd

Contact:+86-021-50792271

Address:Building 24A, 300 Chuantu Road, Chuansha, Pudong new area, Shanghai, China, 201202
Chengdu D-Innovation Pharmaceutical Co., Ltd

Contact:86-28-85105536

Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
zhenjiang runjing high purity chemical co ltd

Contact:+86-511-83361155

Address:No.8.haixi road,international chemical park
Jiangsu Chiatai Qingjiang Pharmaceutical Co.,Ltd

Contact:+86-517-86283327

Address:9 North Hantai Road, Huaian, China

Relevant to this article

USE OF L-ASPARTIC ACID β-SEMIALDEHYDE IN THE SYNTHESIS OF MORE COMPLEX NON PROTEIN AMINO ACIDS

Doi:10.1016/S0040-4039(00)95547-3
(1987)
S-alkylation of thiacalixarenes: A long-neglected possibility in the calixarene family

Doi:10.1021/ol201546y
(2011)
Doi:10.1039/j39680003020
(1968)
Synthesis of 9-β-D-(Xylofuranosyl)adenine from Adenosine

Doi:10.1055/s-1989-27258
(1989)
Doi:10.1007/BF03037359
(1959)
Syntheses and characterization of inorganic-organic hybrids with 4-(isonicotinamido)phthalate and some divalent metal centers

Doi:10.1016/j.poly.2010.05.014
(2010)

Article Doi