Stereoselective synthesis and structural establishment of (25S)-24,24- difluoro-1α,25,26-trihydroxyvitamin D3, a major metabolite of 24,24- difluoro-1α,25-dihydroxyvitamin D3

DOI: 10.1016/S0040-4020(98)00949-1

Source and publish data:

Tetrahedron p. 14705 - 14724 (1998)

Update date:2022-09-26

Topics:

Authors:

Iwasaki, Hiroshi

Hosotani, Ryuzo

Miyamoto, Yoichi

Nakano, Yoshio

Yamamoto, Keiko

Yamada, Sachiko

Shinki, Toshimasa

Suda, Tatsuo

Yamaguchi, Kentaro

Konno, Katsuhiro

Takayama, Hiroaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)00949-1

(25S)-24,24-Difluoro-1α,25,26-trihydroxyvitamin D₃ (3a) and its (25R)- epimer (3b), either of which is expected to be a major metabolite of 24,24- difluoro-1α,25-dihydroxyvitamin D₃ (2), were synthesized. Asymmetric addition to β-ket

Full text of DOI:10.1016/S0040-4020(98)00949-1

Products guided by the article

Product name:(R)-6-{(1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-3,3-difluoro-1-((R)-toluene-4-sulfinyl)-heptan-2-one

Cas No:219123-54-3

R&D Labs maybe for 219123-54-3

Suzhou JMS Chemical Co., Ltd.

Contact:+86-15995924277

Address:WuZhongOu suzhou new south road 89
Hisyntech Corporation Limited

Contact:0086-22-23410962

Address:17-201, Ningfuli, Shuishanggongyuandong road,Nankai district, Tianjin, China
waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
Anyang Double Circle Auxiliary CO.,LTD

Contact:0086-134 6082 4403

Address:dongfeng road, anyang city, henan province,china
Nanjing Zelang Medical Technology Co. Ltd

Contact:86-25-83063290/13770714480

Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China

Relevant to this article

USE OF L-ASPARTIC ACID β-SEMIALDEHYDE IN THE SYNTHESIS OF MORE COMPLEX NON PROTEIN AMINO ACIDS

Doi:10.1016/S0040-4039(00)95547-3
(1987)
S-alkylation of thiacalixarenes: A long-neglected possibility in the calixarene family

Doi:10.1021/ol201546y
(2011)
Doi:10.1039/j39680003020
(1968)
Synthesis of 9-β-D-(Xylofuranosyl)adenine from Adenosine

Doi:10.1055/s-1989-27258
(1989)
Doi:10.1007/BF03037359
(1959)
Syntheses and characterization of inorganic-organic hybrids with 4-(isonicotinamido)phthalate and some divalent metal centers

Doi:10.1016/j.poly.2010.05.014
(2010)

Article Doi