Oxygen Sensitization of Electron Capture Response to Isomers of Polycyclic Aromatic Amines and Hydroxides

Article abstract of DOI:10.1021/ac00259a034

The use of the oxygen-sensitized constant-current electron capture detector (ECD) with gas chromatography for analyte identification is extended by examining the responses of numerous polycyclic aromatic amines and hydroxides where an appropriate EC-enhancing chemical tag has been attached to the amino group or the hydroxy group has been methylated.For the majority of isomeric groups examined, measured response enhancements of the derivatives are sufficiently dependent on structural differences as to provide an additional means by which substitution isomers can be differentiated.The ion chemistry responsible for the EC and oxygen-sensitized responses also has been examined by the use of an atmospheric pressure ionization mass spectrometer (APIMS).