Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonists

DOI: 10.1016/S0960-894X(99)00312-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2059 - 2064 (1999)

Update date:2022-07-30

Topics:

Authors:

Dubuffet, Thierry

Newman-Tancredi, Adrian

Cussac, Didier

Audinot, Valerie

Loutz, Annie

Millan, Mark J.

Lavielle, Gilbert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00312-1

A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D₃ versus D₂ receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D₃ receptor antagonist.

Full text of DOI:10.1016/S0960-894X(99)00312-1

Products guided by the article

Product name:rac S 33138

Cas No:220647-56-3

R&D Labs maybe for 220647-56-3

Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Li's chemicals

Contact:+86-15850770348

Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China
Jiangyin Tenghua Import&Export Co.,Ltd.

Contact:+86-510-86263875

Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
SINFACHEM LIMITED

Contact:86-25-84683399

Address:605, Phoenix Herui Plaza, No.389, South Taiping Road, Nanjing, China 210002
SNC | GOOD FORTUNE

Contact:0086-22-2822 1962 / 2822 1963

Address:B-808, No. 1, North-South Street, Hexi District,

Relevant to this article

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders

Doi:10.1371/journal.pone.0180319
(2017)
Analytical and Sensory Characterization of the Stereoisomers of 3-Mercaptocycloalkanones and 3-Mercaptocycloalkanols

Doi:10.1021/acs.jafc.0c03113
(2020)
Nucleophilic Aromatic Substitution (S_NAr) as an Approach to Challenging Carbohydrate-Aryl Ethers

Doi:10.1021/acs.orglett.5b02413
(2015)
Doi:10.1021/jo01149a028
(1950)
Solid-state NMR, crystallographic and density functional theory investigation of Fe-CO and Fe-CO analogue metalloporphyrins and metalloproteins

Doi:10.1021/ja9832818
(1999)
Resolution of (±)-mandelic- and (±)-2-(chlorophenoxy)propionic-acid derivatives by crystallization of their diastereomeric amides with (R)- or (S)-α-arylethylamines

Doi:10.1016/S0040-4039(99)00169-0
(1999)

Article Doi