Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonists

DOI: 10.1016/S0960-894X(99)00312-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2059 - 2064 (1999)

Update date:2022-07-30

Topics:

Authors:

Dubuffet, Thierry

Newman-Tancredi, Adrian

Cussac, Didier

Audinot, Valerie

Loutz, Annie

Millan, Mark J.

Lavielle, Gilbert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00312-1

A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D₃ versus D₂ receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D₃ receptor antagonist.

Full text of DOI:10.1016/S0960-894X(99)00312-1

Products guided by the article

Product name:rac S 33138

Cas No:220647-56-3

R&D Labs maybe for 220647-56-3

shanghai hekang chemical co.ltd

Contact:021-54173790

Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Suzhou Chenke Biotech Co., Ltd.

Contact:+86-18662408853

Address:NO.150, Renai Road, Suzhou Industrial Park
Beijing eternalchem Co,. Ltd

Contact:+86-10-59484199

Address:No.58-A1026 Liangguan Street
Shanghai Topchem Co., LTD

website:http://www.shtopchem.com/

Contact:0086-0576-87776998

Address:room no 1608,xuhui business building yude road,xujiahui street, xuhui district
CHEMINN LTD.

website:http://www.cheminn.com/

Contact:86-531-67875205

Address:No.9-2,South of Shanda Road, Jinan ,China

Relevant to this article

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders

Doi:10.1371/journal.pone.0180319
(2017)
Analytical and Sensory Characterization of the Stereoisomers of 3-Mercaptocycloalkanones and 3-Mercaptocycloalkanols

Doi:10.1021/acs.jafc.0c03113
(2020)
Nucleophilic Aromatic Substitution (S_NAr) as an Approach to Challenging Carbohydrate-Aryl Ethers

Doi:10.1021/acs.orglett.5b02413
(2015)
Doi:10.1021/jo01149a028
(1950)
Solid-state NMR, crystallographic and density functional theory investigation of Fe-CO and Fe-CO analogue metalloporphyrins and metalloproteins

Doi:10.1021/ja9832818
(1999)
Resolution of (±)-mandelic- and (±)-2-(chlorophenoxy)propionic-acid derivatives by crystallization of their diastereomeric amides with (R)- or (S)-α-arylethylamines

Doi:10.1016/S0040-4039(99)00169-0
(1999)

Article Doi