Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonists

DOI: 10.1016/S0960-894X(99)00312-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2059 - 2064 (1999)

Update date:2022-07-30

Topics:

Authors:

Dubuffet, Thierry

Newman-Tancredi, Adrian

Cussac, Didier

Audinot, Valerie

Loutz, Annie

Millan, Mark J.

Lavielle, Gilbert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00312-1

A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D₃ versus D₂ receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D₃ receptor antagonist.

Full text of DOI:10.1016/S0960-894X(99)00312-1

Products guided by the article

Product name:rac S 33138

Cas No:220647-56-3

R&D Labs maybe for 220647-56-3

HAINAN JINYING IMPORT AND EXPORT CO. LTD

Contact:+86-898-32875423

Address:A SECTION 19TH FL, TIMES SQUARE, NO.2 GUO MAO AVENUE HAIKOU, HAINAN, P. R. OF CHINA
ANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD

Contact:86-561-4080321

Address:No.8 Lieshan Industrial Zone of Huaibei
Taixing Shenfeng Chemical Co., Ltd.

Contact:+86-523-87117033, 87117666

Address:4# Yinsanlu, Huangqiao town, Taixing, Jiangsu, China.
Nanjing Raise Pharmatech Co., Ltd

website:http://www.raisechem.com

Contact:+86-25-58649566

Address:B381,No.606,Ningliu Road,Jiangbei New Area,Nanjing,Jiangsu Province,China
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:No.199, Ningbo Avenue, Fengxin industrial park, Fengxin county, Yichun city, Jiangxi

Relevant to this article

Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders

Doi:10.1371/journal.pone.0180319
(2017)
Analytical and Sensory Characterization of the Stereoisomers of 3-Mercaptocycloalkanones and 3-Mercaptocycloalkanols

Doi:10.1021/acs.jafc.0c03113
(2020)
Nucleophilic Aromatic Substitution (S_NAr) as an Approach to Challenging Carbohydrate-Aryl Ethers

Doi:10.1021/acs.orglett.5b02413
(2015)
Doi:10.1021/jo01149a028
(1950)
Solid-state NMR, crystallographic and density functional theory investigation of Fe-CO and Fe-CO analogue metalloporphyrins and metalloproteins

Doi:10.1021/ja9832818
(1999)
Resolution of (±)-mandelic- and (±)-2-(chlorophenoxy)propionic-acid derivatives by crystallization of their diastereomeric amides with (R)- or (S)-α-arylethylamines

Doi:10.1016/S0040-4039(99)00169-0
(1999)

Article Doi