Effect of cyclohexenonic long chain fatty alcohols on neurite outgrowth. Study on structure-activity relationship

DOI: 10.1016/S0040-4020(98)00406-2

Source and publish data:

Tetrahedron p. 7735 - 7748 (1998)

Update date:2022-07-31

Topics: Neurite Outgrowth Structure-Activity Relationship Experimental Chemical terms Study

Authors:

Girlanda-Junges, Celine

Keyling-Bilger, Florence

Schmitt, Gaby

Luu, Bang

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)00406-2

Four series of long chain fatty alcohols bearing a cyclohexenone moiety in addition to a ω-alkanol side chain were synthesized using 'Umpolung' reactivity strategy. Their effect on neurite outgrowth was evaluated by means of fetal rat neurons in culture. The length of the ω-hydroxy side chain is a crucial factor for biological activity.

Full text of DOI:10.1016/S0040-4020(98)00406-2

Products guided by the article

Product name:4,4-dimethyl-1,1-(ethylenedioxy)-3-(phenylsulfonyl)-cyclohexane

Cas No:220757-94-8

R&D Labs maybe for 220757-94-8

Nanjing Yuance Industry&Trade Co., Ltd.

website:http://www.njyuance.cn/

Contact:+86-25-85439097

Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Jingzhou TianHe Sci&Tech Chemical Co., Ltd.

Contact:86-716-8331612

Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Shandong Shouguang Songchuan Industrial Additives Co.,Ltd

Contact:+86-536-8566856

Address:Shouguang,Shandong,China

Relevant to this article

Synthesis, solution dynamics, and x-ray crystal structure of bis(2,4,6-tris(trifluoromethyl)-phenyl)(1,2-dimethoxyethane)nickel

Doi:10.1021/om0100784
(2001)
Synthesis of enantiomerically pure (2S)-2-endo-hydroxymethyl-5- norbornene by Diels-Alder reaction based on a new fructose-derived auxiliary

Doi:10.1021/jo982023q
(1999)
A new approach to the synthesis of 2-aminoimidazo[1,2-α]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines

Doi:10.1016/S0040-4020(99)00012-5
(1999)
Synthesis of fully-substituted enediynes by the corey-winter reaction

Doi:10.1080/00397919908085778
(1999)
Aryl-substituted triazines with antidepressant activity.

Doi:10.1021/jm00302a013
(1969)
Octadehydromichellamine, a structural analog of the anti-HIV michellamines without centrochirality

Doi:10.1016/S0040-4020(98)01195-8
(1999)

Article Doi