A new approach to the synthesis of 2-aminoimidazo[1,2-α]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines

DOI: 10.1016/S0040-4020(99)00012-5

Source and publish data:

Tetrahedron p. 2317 - 2326 (1999)

Update date:2022-07-31

Topics:

Authors:

Vega, Juan A.

Vaquero, Juan J.

Alvarez-Builla, Julio

Ezquerra, Jesus

Hamdouchi, Chafiq

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Article abstract of DOI:10.1016/S0040-4020(99)00012-5

A microwave (focused waves) assisted N-alkylation of 2-halopyridines provides a convenient entry to 2-amino-imidazo[1,2-a]pyridine derivatives after reaction of the alkylated substrates with cyanamide under basic conditions.

Full text of DOI:10.1016/S0040-4020(99)00012-5

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