New nucleoside heteroanalogues: Desoxynucleoside selenocyanates

Article abstract of DOI:10.1016/S0040-4039(98)02559-3

New nucleoside heteroanalogues, 5' and 3'-desoxynucleoside selenocyanates and primary desoxysugar selenocyanates, were synthesized from activated nucleoside and sugar derivatives and a new convenient seleno nucleophile, tetrabutylammonium selenocyanate. Tresylate-based activation of hydroxy functions turned out to be most successful for formation of theme selenocyanates compared with mesylate- or triflate-based activation.