Bioorganic and Medicinal Chemistry Letters p. 623 - 626 (1999)
Update date:2022-08-03
Topics:
Barber, Amelia Moreno
Hardcastle, Ian R.
Rowlands, Martin G.
Nutley, Bernard P.
Marriott, Jonathan H.
Jarman, Michael
A novel diphosphate mimic, the 2,3,6-trifluoro-5-hydroxy-4-nitrophenoxy group (1), has been employed as the template in the solid-phase synthesis of novel Farnesyl Transferase inhibitors using the Mitsunobu reaction. The most potent inhibitor (famesyloxy-
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Doi:10.1002/jccs.199900007
(1999)Doi:10.1021/acs.joc.8b01441
(2018)Doi:10.1021/jo00827a001
(1970)Doi:10.1039/C8CC07125J
(2018)Doi:10.1021/jo0495586
(2004)Doi:10.1016/0040-4039(94)88459-5
(1994)
