Solid-phase synthesis of N,N'-unsymmetrically substituted ureas: Application to the synthesis of carbaza peptides

Article abstract of DOI:10.1016/S0040-4039(99)00288-9

The synthesis of Boc- or Fmoc-monoprotected propylenediamine derivatives is reported starting from N-protected α-amino acids. The introduction of these building blocks on solid support via the formation of a urea moiety leads to a new pseudopeptide family