Chemical and Pharmaceutical Bulletin p. 1366 - 1375 (1992)
Update date:2022-07-31
Topics:
Liu
Kiuchi
Tsuda
The structure of gymnemagenin (3β,16β,21β,22α,23,28-hexahydroxy-olean-12-ene), the sapogenin of the antisweet principles of Gymnema sylvestre, was established by X-ray analysis of the 3β,23;21β,22α-di-O-isopropylidene derivative. On the basis of this result, the structure of deacylgymnemic acid was elucidated as the 3-O-β-glucuronide from the carbon-13 nuclear magnetic resonance spectra. Five antisweet principles, gymnemic acid-III, -IV, -V, -VIII, and -IX, were isolated in pure states from the hot water extract of leaves of Gymnema sylvestre. Of these, three (GA-III, -IV, and -V) were known, while two (GA-VIII and-IX) were new compounds. The structures of GA-VIII and -IX were elucidated as 3'-O-β-D-arabino-2-hexulopyranosyl gymnemic acid-III and -IV, respectively.
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(1997)Doi:10.1016/S0040-4039(01)98951-8
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(1962)Doi:10.1021/ja01634a050
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