Journal of Heterocyclic Chemistry p. 97 - 104 (1999)
Update date:2022-08-03
Topics: Acylation Regioselectivity Column chromatography Yield NMR spectroscopy Catalyst Deprotonation Recrystallization Mass spectrometry (MS) Pyrimidine Nucleophilic addition HPLC (high-performance liquid chromatography) Michael addition Tautomerization Biginelli Reaction Solvent Evaporation Cyclocondensation Reaction reflux
Vedernikova, Irina V.
Haemers, Achiel
Ryabukhin, Yuryi I.
The synthesis of N1-substituted 4-pyrimidones is described. These compounds were prepared from their corresponding 4-oxopyrimidinium perchlorates or from a reaction of a primary amine with a N-acyl-β- ketoamide.
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