Scorzonerosides A, B and C, novel triterpene oligoglycosides with hepatoprotective effect from Chinese Bupleuri radix, the roots of Bupleurum scorzonerifolium Willd.

Article abstract of DOI:10.1016/S0040-4039(97)01733-4

Triterpene glycoside adonitol esters, scorzonerosides A, B, and C, were isolated from Chinese Bupleuri Radix, the roots of Bupleurum scorzonerifolium. Their absolute stereostructures were elucidated on the physicochemical and chemical evidence, which included the synthesis of the adonitol moiety from D-ribose. Scorzonerosides A, B, and C were found to show hepatoprotective effect on liver injury induced by D-galactosamine and lipopolysaccharide in mice.